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By R. Pant J. P. Fielding

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Free-running rhythms close to 24 hours were then demonstrated in many different animals and plants, so that a collective term was needed to describe such phenomena. circadiaN sysTeM aNd diurNal acTiviTy It was Halberg who suggested that they should be called circadian rhythms. However, circadian rhythms are not the only biological clock-driven rhythms observed in nature. Other rhythms have been defined on the basis of their period under constant conditions and relatedness to environmental cycles.

Cognition, 79, 1–37. C. 1970. Facing Reality: Philosophical Adventures by a Brain Scientist. Berlin: Springer-Verlag. C. 1994. How the Self Controls its Brain. Berlin: Springer-Verlag. , Meairs, S. et al. 2008. Improving outcome after stroke: Overcoming the translational roadblock. Cerebrovascular Disease, 25, 268–78. F. and Bailey, P. 1929. Tumors in the region of the third ventricle: Their diagnosis and relation to pathological sleep. The Journal of Nervous and Mental Disease, 69, 1–25. , Grosman-Rimon, L.

1 generalized phase response curve of the circadian system Illustrates the response to light administration at different phases of the circadian cycle. g. g. getting-up earlier the following day after the light exposure). The ‘dead zone’ represents a period of relative insensitivity to light. Under normal circumstances morning light (0/24h) advances the clock whist evening light (Dusk ~ 12h) delays the clock. In this manner circadian activity is appropriately aligned to the dawn/dusk cycle. circadiaN sysTeM aNd diurNal acTiviTy not provide a complete description of entrainment.

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Aircraft configuration and flight profile optimization using simulated annealing by R. Pant J. P. Fielding

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